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Asthisamharaka (Vitis quadrangularis): A Medicinal Plant with Promising Health Benefits and Therapeutic Potential

Introduction: Asthisamharaka (Vitis quadrangularis), also known as the Devil's Backbone or Hadjod, is a medicinal plant that has been widely used in traditional medicine systems for centuries. With its origins in India, this plant belongs to the Vitaceae family and is characterized by its unique four-angled stem. Hadjod holds significant importance in various cultures due to its potential health benefits and therapeutic properties. Its traditional use can be traced back to ancient Ayurvedic texts, where it is highly regarded for its ability to promote bone health and treat musculoskeletal disorders. Historically, Hadjod has been used as a natural remedy for fractures, bone loss, and joint-related conditions. In Ayurveda, it is classified as a 'Asthisandhaneeya' herb, meaning it has the potential to strengthen bones, promote fracture healing, and improve overall bone health. The plant's name, "Hadjod," is derived from the Hindi word "hadjod,"

Lakshadi Guggulu: Harnessing the Power of Ayurveda for Bone Health and Musculoskeletal Wellness


Ayurveda, the ancient Indian system of medicine, has long been revered for its holistic approach to health and well-being. Rooted in nature and emphasizing the balance of mind, body, and spirit, Ayurveda offers a wealth of traditional remedies that have stood the test of time. One such prominent herbal formulation in Ayurvedic medicine is Lakshadi Guggulu. Derived from a blend of potent herbs, Lakshadi Guggulu holds a special place in Ayurveda for its therapeutic properties and wide-ranging health benefits. Let us delve into the world of Lakshadi Guggulu and discover the wonders it holds for our well-being.

Overview of Lakshadi Guggulu:

Lakshadi Guggulu is a renowned herbal formulation deeply rooted in Ayurveda, the ancient Indian system of medicine. Its history can be traced back to thousands of years, where it finds mention in classical Ayurvedic texts like the Charaka Samhita and Sushruta Samhita. Traditionally, it has been used for its remarkable healing properties, particularly in the management of musculoskeletal disorders and bone-related conditions.

The composition of Lakshadi Guggulu consists of a synergistic blend of several potent herbs. The primary ingredient is Guggulu, a resin obtained from the Commiphora mukul tree. Guggulu is known for its anti-inflammatory, analgesic, and rejuvenating properties. Other key ingredients commonly found in Lakshadi Guggulu include Laksha (Laccifer lacca), Ashwagandha (Withania somnifera), Arjuna (Terminalia arjuna), and Guduchi (Tinospora cordifolia). These herbs work together to enhance the efficacy of the formulation and promote overall well-being.

According to Ayurveda, Lakshadi Guggulu is classified as a Guggulu-based formulation. Guggulu preparations are renowned for their ability to penetrate deep into the tissues and deliver therapeutic effects. Lakshadi Guggulu is primarily known for its Vata-balancing and bone-strengthening properties. It is believed to nourish and strengthen the bones, joints, and connective tissues, making it an invaluable remedy for conditions like osteoarthritis, osteoporosis, fractures, and joint pain.

In addition to its bone-related benefits, Lakshadi Guggulu is also believed to have a rejuvenating effect on the entire musculoskeletal system. It helps alleviate inflammation, reduce swelling, and improve joint mobility. Furthermore, it is considered beneficial for promoting healthy digestion and supporting the detoxification processes in the body.

Overall, Lakshadi Guggulu holds a prominent place in Ayurveda due to its historical significance, traditional use, and therapeutic properties that contribute to the well-being of individuals seeking natural remedies for musculoskeletal health.

Health Benefits of Lakshadi Guggulu:

Lakshadi Guggulu offers a wide range of health benefits, particularly in promoting bone health and addressing musculoskeletal disorders. Let's delve into its therapeutic effects:

Promotes Bone Health and Treats Musculoskeletal Disorders:

Lakshadi Guggulu is renowned for its ability to nourish and strengthen the bones. It aids in maintaining healthy bone density and supports the overall skeletal system. Regular use of Lakshadi Guggulu can be beneficial for individuals with conditions such as osteoporosis, osteoarthritis, and other degenerative bone disorders.

Manages Joint Pain, Inflammation, and Arthritis:

The anti-inflammatory properties of Lakshadi Guggulu help reduce joint inflammation and relieve pain associated with various musculoskeletal conditions. It is often used as an adjunct therapy in managing arthritis, rheumatism, and gout. The formulation works by alleviating swelling, improving joint mobility, and reducing discomfort.

Aids in Fracture Healing:

Lakshadi Guggulu plays a vital role in supporting fracture healing. It helps enhance the natural healing process of bones and assists in the proper union of fractured bone segments. The formulation aids in strengthening the affected bones, reducing pain, and expediting the recovery time.

Supports Overall Bone Strength:

By nourishing the bones and promoting healthy bone tissue regeneration, Lakshadi Guggulu contributes to overall bone strength. It helps prevent conditions like osteopenia and osteoporosis, which are characterized by weak and brittle bones. Regular use of Lakshadi Guggulu can be beneficial in maintaining optimal bone health and preventing age-related bone degeneration.


It's important to note that while Lakshadi Guggulu offers potential benefits for bone health and musculoskeletal disorders, individual results may vary. It is advisable to consult with a qualified Ayurvedic practitioner or healthcare professional before incorporating Lakshadi Guggulu into your healthcare regimen, especially if you have any underlying medical conditions or are taking medications.

Mode of Action:

Lakshadi Guggulu exerts its therapeutic effects through a combination of its ingredients and their synergistic actions. Here's an insight into its mode of action:

Synergistic Effects of Ingredients:

The herbs present in Lakshadi Guggulu work together to enhance its therapeutic properties. Guggulu, the primary ingredient, possesses anti-inflammatory and analgesic properties, which help alleviate pain and reduce inflammation in the joints and tissues. Laksha (Laccifer lacca) contributes to bone regeneration and healing. Ashwagandha (Withania somnifera) has anti-inflammatory and immunomodulatory effects, supporting joint health and relieving inflammation. Arjuna (Terminalia arjuna) aids in strengthening the bones and promoting healthy cardiovascular function. Guduchi (Tinospora cordifolia) acts as an immunomodulator, promoting the body's natural defense mechanisms. The combination of these ingredients enhances the overall efficacy of Lakshadi Guggulu.

Impact on the Doshas:

According to Ayurveda, the doshas—Vata, Pitta, and Kapha—are the fundamental energetic principles governing the body. Lakshadi Guggulu is primarily known for its Vata-balancing properties. Vata dosha governs the movement and function of the musculoskeletal system. Imbalances in Vata can lead to joint pain, stiffness, and inflammation. Lakshadi Guggulu helps pacify excessive Vata, thereby reducing these symptoms. It aids in lubricating the joints, improving mobility, and promoting the overall well-being of the musculoskeletal system.


Additionally, Lakshadi Guggulu has a balancing effect on Pitta and Kapha doshas. Pitta dosha is associated with inflammation and heat, while Kapha dosha is associated with heaviness and stagnation. The formulation's anti-inflammatory and detoxifying properties help balance these doshas, reducing inflammation and promoting optimal functioning of the body.

By addressing imbalances in the doshas, Lakshadi Guggulu aims to restore harmony and balance to the body, promoting overall health and well-being.

It's important to note that the mode of action of Lakshadi Guggulu is complex and multifaceted. The described mechanisms provide a general understanding of its effects, but individual responses may vary. It is always recommended to consult with an experienced Ayurvedic practitioner or healthcare professional for personalized guidance and advice.

Usage and Dosage:

Lakshadi Guggulu can be taken in different forms, such as tablets, powders, or decoctions. The specific dosage and usage guidelines may vary depending on factors such as age, body constitution, and the severity of the condition. It is always best to consult an Ayurvedic practitioner for personalized advice. However, here are some general guidelines:


Lakshadi Guggulu is commonly available in tablet form. The recommended dosage is typically 1-2 tablets, two to three times a day. The tablets can be taken with warm water or milk after meals.


Some formulations of Lakshadi Guggulu may come in powder form. The general dosage is around 1-3 grams, taken two to three times a day. The powder can be mixed with warm water, honey, or ghee to form a paste or consumed directly with water.


In certain cases, Lakshadi Guggulu may be prepared as a decoction. This involves boiling the herbal mixture in water until it reduces to a concentrated liquid. The decoction is usually consumed in a dose of 30-60 ml, two to three times a day.

Ayurvedic Proprietary Medicines with Lakshadi Guggulu:

In addition to the traditional form of Lakshadi Guggulu, Ayurvedic medicine also offers proprietary formulations that combine Lakshadi Guggulu with other potent herbal ingredients. One such example is "Ashvagandha Plus," an Ayurvedic product that harnesses the benefits of both Ashvagandha extract and Lakshadi Guggulu. Let's take a closer look at this formulation:

Ashvagandha Plus:

Active Ingredients:

·        Ashvagandha Extract (Withania somnifera): 250 mg

·        Lakshadi Guggulu: 125 mg

Ashvagandha Plus combines the powerful adaptogenic properties of Ashvagandha with the bone-strengthening and anti-inflammatory effects of Lakshadi Guggulu. Ashvagandha extract is known for its ability to support stress management, enhance vitality, and promote overall well-being. Lakshadi Guggulu, on the other hand, complements these effects by contributing to bone health, joint support, and musculoskeletal wellness.

This proprietary formulation aims to provide a comprehensive solution for individuals seeking the benefits of both Ashvagandha and Lakshadi Guggulu in a convenient and synergistic blend. It is important to note that the specific dosage and usage guidelines for "Ashvagandha Plus" may vary, and it is advisable to follow the instructions provided by the ayurvedic manufacturer or consult with an Ayurvedic practitioner.

Precautions and Contraindications:

While Lakshadi Guggulu is generally considered safe, it is important to be aware of certain precautions and contraindications:

Pregnancy and Lactation: Lakshadi Guggulu should be used with caution during pregnancy and lactation. It is advisable to consult an Ayurvedic practitioner before using it during these stages.

Underlying Medical Conditions: Individuals with pre-existing medical conditions such as diabetes, hypertension, or liver disorders should exercise caution and seek professional guidance before starting Lakshadi Guggulu or any herbal supplement.

Allergies and Sensitivities: If you have known allergies or sensitivities to any of the ingredients in Lakshadi Guggulu, it is important to avoid its use.

Drug Interactions: Lakshadi Guggulu may interact with certain medications. If you are currently taking any prescription medications, it is essential to consult with a healthcare professional to avoid potential interactions.

Remember, the information provided here is for general understanding, and individual requirements may vary. Seeking professional advice ensures the best possible outcomes and ensures that Lakshadi Guggulu is used in a manner suitable for your specific health circumstances.

Research and Scientific Evidence:

While traditional knowledge and historical usage form the foundation of Ayurvedic medicine, it is important to note that scientific research on specific Ayurvedic formulations like Lakshadi Guggulu is still developing. Here is a summary of the available scientific research and emerging trends:

Effectiveness and Safety:

While there is limited clinical research specifically focused on Lakshadi Guggulu, studies have explored the efficacy and safety of its individual ingredients and similar Guggulu-based formulations. For example, Guggulu has been extensively studied for its anti-inflammatory and analgesic properties, supporting its potential benefits in managing musculoskeletal conditions. Other ingredients like Ashwagandha and Arjuna have also been investigated for their bone-strengthening and anti-inflammatory effects.

Ongoing Research and Emerging Trends:

Research on Ayurvedic formulations, including Lakshadi Guggulu, continues to evolve. Ongoing studies aim to explore its therapeutic potential, evaluate its efficacy in various health conditions, and further understand its mode of action.

Emerging trends in Lakshadi Guggulu research include investigations into its anti-inflammatory effects, potential role in managing arthritis and osteoporosis, and its impact on bone health. Additionally, researchers are exploring methods to enhance the bioavailability and standardization of Lakshadi Guggulu to ensure consistent quality and potency.


It is worth noting that scientific research on Ayurvedic formulations often faces challenges due to factors such as the complex nature of multi-herb formulations, the need for standardization, and variations in preparation methods. However, continued scientific inquiry and collaboration between traditional knowledge and modern research methodologies are paving the way for a deeper understanding of Ayurvedic formulations like Lakshadi Guggulu.

As research on Lakshadi Guggulu progresses, it is important to stay updated with the latest scientific findings. Consulting with qualified practitioners who have knowledge of both traditional Ayurvedic principles and contemporary research can help ensure informed decisions about the use of Lakshadi Guggulu and its potential benefits.


In conclusion, Lakshadi Guggulu holds a significant place in Ayurveda as a herbal formulation with potential benefits for bone health and musculoskeletal conditions. Throughout this article, we explored various aspects of Lakshadi Guggulu, including its historical background, composition, therapeutic properties, and mode of action.

Key points to recap:

·        Lakshadi Guggulu is an Ayurvedic herbal formulation with a rich historical background and traditional use in addressing musculoskeletal disorders and promoting bone health.

·        The formulation consists of synergistic ingredients like Guggulu, Laksha, Ashwagandha, Arjuna, and Guduchi, which contribute to its therapeutic properties.

·        Lakshadi Guggulu is known for its Vata-balancing, bone-strengthening, and anti-inflammatory effects. It supports joint health, manages pain and inflammation, aids in fracture healing, and promotes overall bone strength.

·        The mode of action involves the synergistic effects of its ingredients, which work together to restore balance and promote well-being. Lakshadi Guggulu also has an impact on the doshas, particularly Vata, Pitta, and Kapha.


While scientific research on Lakshadi Guggulu is still developing, emerging trends and ongoing studies aim to explore its effectiveness and safety further. It is essential to consult with an Ayurvedic practitioner or healthcare professional before incorporating Lakshadi Guggulu or any herbal supplement into your healthcare regimen.



The information provided here is for informational purposes only and should not replace professional medical advice. Always consult a qualified healthcare practitioner for personalized guidance.

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